Plant extract-loaded bacterial cellulose composite membrane for potential biomedical applications

Plant extract-loaded bacterial cellulose composite membrane for potential biomedical applications

Blog Article

Bacterial cellulose (BC) has been extensively explored as biomaterial for various biomedical applications owing to its non-toxic nature and unique structural morphology and impressive physico-chemical and mechanical properties.However, its high production cost and lack of antimicrobial activity have restricted its large-scale production and therapeutic applications.Therefore, the current study is aimed to devise a strategy for low-cost BC production and develop its composite with bioactive materials to bless it with antimicrobial activity.

Herein, 5 mm thick reticulated fibrous and highly porous BC was produced by utilizing the wasted rotten tomatoes as the production medium.The produced bacterial cellulose waste (BCW) (i.e.

, produced Rugby - Shoes - Mens from wastes) was ex-situ modified with bioactive plant extract (PE) obtained from Euclea schimperi, and the bactericidal activity of the developed BCW/PE was evaluated against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli through disc diffusion and colony forming unit (CFU) count methods.The BCW/PE composite showed high bactericidal activities against S.aureus and produced clear inhibition zone whereas negligible activity was observed against E.

coli, indicating its bactericidal activity mainly against the Gram-positive bacterium.Overall, this study illustrates that there is a huge potential for developing valuable biomaterials from food wastes and utilizing their liquid holding capabilities for value-added applications in medical and Cushion pharmaceutical fields.